Abstract
Typhoid fever in Pakistan: a recurring challenge?
Highlights
Authors Vitorino Modesto dos Santos Armed Forces Hospital and Catholic University, Brasília-DF, Brazil. and Catholic University, Brasília-DF, Brazil. https://orcid.org/0000-0002-7033-6074
Worthy of note is a complete resistance to fluoroquinolones which is associated to prolonged fever and treatment failures of patients with typhoid fever (TF)
The conclusive comments included the need for constant monitoring of antimicrobials sensitivity, with corrective measures to avoid the irrational use of fluoroquinolones (2)
Summary
Authors Vitorino Modesto dos Santos Armed Forces Hospital and Catholic University, Brasília-DF, Brazil. and Catholic University, Brasília-DF, Brazil. https://orcid.org/0000-0002-7033-6074. Authors Vitorino Modesto dos Santos Armed Forces Hospital and Catholic University, Brasília-DF, Brazil. Julia Campos-Modesto Medical Course of Catholic University, Brasília-DF, Brazil. Approximately 1,000 cases per 100,000 children have been reported annually, and patients infected by MDR and XDR S. Typhi in 149 children aged 3-12 years and with TF. High fever of gradual onset, and temperature-pulse dissociation (Faget sign) were emphasized as classical signs of TF; as well as usual manifestations in children including vomiting, diarrhea, anemia, thrombocytopenia and hepatosplenomegaly (2). Worthy of note is a complete resistance to fluoroquinolones (including gatifloxacin after 2010) which is associated to prolonged fever and treatment failures of patients with TF. The conclusive comments included the need for constant monitoring of antimicrobials sensitivity, with corrective measures to avoid the irrational use of fluoroquinolones (2).
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
