Abstract

Autoimmune polyglandular syndromes (APSS) are associations of two or more endocrine diseases of autoimmune origin that affect between 5-10% of the population. The grouping of these diseases depends on genetic and environmental factors, their different presentations allow the distinction of the subtypes of APS. The objective is to report the case of a patient with type III A polyglandular autoimmune syndrome, characterized by Hashimoto's thyroiditis and type 1 diabetes mellitus associated with hyperprolactinemia and Gilbert's syndrome. The patient began to show the symptoms of the syndrome at the age of 10 progressively. The treatment of each disease is being carried out, with no specific treatment for the syndrome in the literature.

Highlights

  • Palabras clave: Síndrome poliglandular autoinmune tipo III; Diabetes mellitus tipo 1; Tiroiditis de Hashimoto; Hiperprolactinemia y Síndrome de Gilbert. It will be reported a case of a 10-years-old Brazilian patient with autoimmune polyglandular syndrome type III A with Hashimoto's thyroiditis associated with type 1 Diabetes Mellitus (DM1)

  • Type III is characterized by the presence of autoimmune thyroid disease (ATD) associated with other autoimmune diseases excluding the involvement of the adrenal gland

  • The aim of this work is to report the case of a patient with type III A polyglandular autoimmune syndrome, characterized by Hashimoto's thyroiditis and type 1 diabetes mellitus plus hyperprolactinemia and Gilbert's syndrome

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Summary

Introduction

It will be reported a case of a 10-years-old Brazilian patient with autoimmune polyglandular syndrome type III A with Hashimoto's thyroiditis associated with type 1 Diabetes Mellitus (DM1). Autoimmune polyglandular syndromes (APSS) are associations of two or more endocrine diseases of autoimmune origin and their different presentations allow the distinction between APS subtypes. Type III is characterized by the presence of autoimmune thyroid disease (ATD) associated with other autoimmune diseases excluding the involvement of the adrenal gland. The patient belongs to group A represented by the association between ATD and DM

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