Abstract

Two cases of insulinoma of which locations were successfully determined preoperatively are reported. Both two patients were admitted to our hospital because of loss of consciousness, and were suspected to have insulinomas by fasting blood sugar levels and blood immuno reactive insuline levels.Ultrasonography, percutaneous transhepatic portal catheterization (PTPC), angiography and dynamic computed tomography showed that the tumors were solitary insulinomas arising in the head of the pancreas. By using intraoperative ultrasonography, the tumors could be removed not to damage the main pancreatic duct. The only curative treatment for the insulinoma is complete excision of the tumor. However, these tumors are often small and some are multiple, in that we have difficulties to determine their locations. Greater efforts using ultrasonography, CT, PTPC, and angiography combinedly would be necessary.

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