Abstract
Cysteine (Cys) plays an important role in many physiological and pathological processes, and is closely related to many diseases. Therefore, it is necessary to develop fluorescent probes that specifically monitor Cys in vivo, which also helps to further understand the pathological process of related diseases. However, the fluorescent probes reported so far rarely distinguish Cys from the other two biothiols. Therefore, a fluorescent probe with high selectivity and excellent cell membrane permeability, (E)-3-(6-bromopyridin-2-yl)-1-(pyren-3-yl)prop-2-en-1-one (Probe), has been designed for monitoring endogenous and exogenous Cys in HeLa cells.
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