Abstract
Tungsten (W) microelectrodes were made with a taper of the tip of about 1∶10 and insulated with lacquer leaving a tip length of about 10–100 μm. The resting potential in saline was about −0·3 V relative to an Ag/AgCl reference electrode for input currents <10−12 A. The small signal impedance was ideally that of a capacitor 0·4 pF/μm2 between 10 Hz and 1000 Hz. Imperfect insulation at the tip caused this impedance to be increasingly resistive. The voltage response to positive and negative current pulses was symmetrical for currents up to 10−8 A. The results obtained in the brain of the conscious monkey and the anaesthetised frog were similar to those obtained in the salines. The electrochemical properties of tungsten were studied using macroelectrodes: the metal behaves as an inert metal within the potentials where it is usually used in biological experiments.
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