Abstract

Demonstration of brain parenchyma at the base of the skull and in the cerebellum in CT studies is usually rendered difficult by the partial volume effect of adjacent bone structures. As a result, studies by a number of authors have shown the superiority of MRI over CT in demonstrating brain tumors at these locations in adults (8, 9, 10, 15, 16, 22, 23). Signal enhancement with paramagnetic contrast media has played an important role in this respect (6, 7, 17). The fact that there is no exposure to X-ray is an additional advantage of MRI in studies of children and adolescents. This important advantage has to be weighed against the long duration of the examination and necessity of sedation or general anesthesia in infants and young children. Since gadolinium cannot be administered to young children, we undertook to compare CT and MRI in children with tumors at the base of the skull and in the posterior fossa.

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