Abstract
Guinea pig serum (GPS) has been shown (1–3) to inhibit the growth of the Gardner lymphosarcoma 6C3HED in C3H mice, as well as certain other tumors (1,2). Broome (4) has presented evidence recently that the L-asparaginase activity of GPS is responsible for the anti-lymphoma effect. The experiments described here on the effectiveness of partially purified L-asparaginase of GPS in inhibiting tumor growth support Broome's proposal.
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