Tu1175 STANDART VERSUS INTENSIFIED BOWEL PREPARATION FOR MORNING COLONOSCOPY

Abstract

Colonoscopy with polypectomy reduces colorectal cancer incidence and mortality. An adequate bowel preparation (BP) is essential for procedure success, is considered an important quality measure for colonoscopy service and allows for long intervals between examinations in subjects with normal examinations. Inadequate preparation occurs in up to 30% of patients undergoing colonoscopy and is associated with increased procedure time, need for repeated procedure, lower cecal intubation rates and lower polyp and adenoma detection rates. Currently there is no data on BP quality following intense bowel preparation protocol combining Picosalax and Polyethylene Glycol. To check if an intensified BP regimen leads to a significant improvement in BP quality. A single center, retrospective observational study. 176 patients referred for morning endoscopic mucosal resection (EMR) received intensified BP (two split doses of Sodium Picosulfate / Magnesium Oxide / Citric Acid (Picosalax) with one dose (1500 cc) of polyethylene glycol between them). This group was compared with 208 ambulatory patients having morning colonoscopy following standard split-dose BP with Picosalax. Bowel preparation quality was assessed with the Boston Bowel Preparation Score (BBPS). Failed BP was defined as a colon segments with a score of 1 or a global score below 6. The mean BBPS was similar in both groups. However, the rate of failed BP was significantly lower in patients who had an intensified BP, both overall and per colon segments. In this retrospective study, intensified BP reduced failed BP rates compared with standard split-dose BP.View Large Image Figure ViewerDownload Hi-res image Download (PPT)