Abstract
Urinary excretion of t ryptophan metabolites, etiocholanolone, androsterone, and 17-hydroxycorticosteroids (17-OHc.s.), was measured in 25 patients with breast cancer a n d i n 12 similarly aged control women. Twelve of the 25 patients had elevated excretions of metabolites of the kynurenine-niacin pa thway, and, in these patients, t he excretion of etiocholanolone was significantly lower t h a n in controls or in patients with normal t ryp tophan metabolism.
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