Abstract
Tryptophan capped gold-silver bimetallic nanoclusters (Trp-Au/Ag BNCs) based turn-off fluorescence sensor has been developed for the simple and rapid determination of histamine. Sensor parameters such as the effect of solvent, irradiation time etc. were optimized and further studies were done using these results. Fluorescence quenching of BNCs happens with the incremental addition of histamine. This might be due to the aggregation of BNCs induced by the electrostatic force of attraction between the negatively charged BNCs and amino functional groups of histamine. The sensor showed good sensitivity for the determination of histamine with a linear range of 8.5 × 10−5 M to 4.0 × 10−6 M and a limit of detection (LOD) of 9.0 × 10−7 M. Practical utility of the proposed sensor has been proved through spike recovery analysis in synthetic physiological fluids.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
