Abstract

Trinuclear Schiff base complexes were synthesized by using p-phenylene diamine, 2,3-pentanedione and 3-aminocoumarin and Cu (II), Ni (II), Mn (II), Zn(II) and Cr(III) chloride salts. The category of compound was [M3LCl6]. All trinuclear compounds were analyzed by C, H&N analysis and spectral studies. Mechanism of thermal analysis of trinuclear Schiff base metal complexes was studied. The electrophoresis data confirmed that Schiff base compounds cleaved DNA with Hydrogen peroxide. Additionally, the antibacterial action was tested by disc diffusion method. The efficiency of compounds was assessed against selected microbes. The result of minimum inhibitory concentration confirmed that trinuclear Schiff base metal compounds have got more efficiency.

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