Abstract

Male albino mice were infected orally with 450 ± 10 excysted Trichinella spiralis larvae. Between Days 6 and 11 after infection, adults were collected from the intestine and incubated in vitro. The females shed first-stage migratory larvae which were collected and placed in a migratory chamber. The larvae showed a definite ability to respond to a microenvironmental stimulus. The taxis was positive ( p < 0.025) to a 120-mV stimulus simulating the skeletal muscle action potential and to a 120-mV polar stimulus ( p < 0.005). There was a negative taxis ( p < 0.005) to a 95-mV stimulus simulating the resting skeletal muscle potential and to a KCl gradient. A significant ( p < 0.05) distribution occurred to a lactic acid gradient, and there were no taxes ( p > 0.05) to either glycogen or phosphocreatine.

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