Abstract
BackgroudDiabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally.MethodsData on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASIR) of diabetes mellitus according to sex, region, and disease type.ResultsThe worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASIR increased from 234 /100,000 persons (95% UI, 219–249) to 285/100,000 persons (95% UI, 262–310) in this period [EAPC = 0.87, 95% confidence interval (CI):0.79–0.96]. The global ASIRs of T1DM and T2DM both demonstrated significant increase during 1990–2017, with EAPCs of 0.34 (95% CI,0.30–0.39) and 0.89 (95% CI,0.80–0.97), respectively. The ASIR trends also varied considerably by regions and countries. The increase in ASIR was greatest in high sociodemographic index regions (EAPC = 1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC = 0.79, 95% CI:0.71–0.88).ConclusionsBoth the number of incident cases and ASIR of diabetes mellitus increased significantly during 1990–2017 worldwide, but the temporal trends varied markedly across regions and countries.
Highlights
Studies have shown that the incidence of type 1 diabetes mellitus (T1DM) increased worldwide over the past 3 decades [3,4,5]
The worldwide incident cases of diabetes mellitus increased by 102.9%, from 11,303 × 103 (95% Uncertainty Interval (UI), 10,582 × 103–12,102 × 103) in 1990 to 22,936 × 103 (95% UI, 21, 083 × 103–25,041 × 103) in 2017
The global agestandardized incidence rate (ASIR) increased from 234/100,000 persons (95% UI, 219–249) in 1990 to 285/100,000 persons (95% UI, 262–310) in 2017 (EAPC = 0.87, 95% confidence interval (CI): 0.79–0.96) (Table 2)
Summary
We aimed to determine the temporal and geographical trends of diabetes globally
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
