Abstract
The proportion of patients with cancers who develop invasive fungal infections has increased dramatically over the past few decades. most of these infections are diagnosed in patients with hematological malignancies, mainly in patients with acute myeloid leukemia and those under-going allogeneic hematopoietic stem cell transplantation. for years deoxycolate amphotericin b has been considered the drug of choice for the treatment of invasive as-pergillosis, but it has been outclassed by its lipid formulations and new triazoles (i.e. voriconazole), that produced better response rates; nonetheless recovery from neutropenia remains the most important factor influencing outcome.
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