Abstract

Treatment for sialolithiasis has undergone significant changes since the 1990s. Following the development of new minimally invasive and gland-preserving treatment modalities, a 40–50% rate of gland resection was reduced to less than 5%. Extracorporeal shock-wave lithotripsy (ESWL), refinement and extension of methods of transoral duct surgery (TDS), and in particular diagnostic and interventional sialendoscopy (intSE) are substantial parts of the new treatment regimen. It has also become evident that combining the different treatment modalities further increases the effectiveness of therapy, as has been especially evident with the combined endoscopic–transcutaneous approach. In the wake of these remarkable developments, a treatment algorithm was published in 2009 including all the known relevant therapeutic tools. However, new developments have also taken place during the last 10 years. Intraductal shock-wave lithotripsy (ISWL) has led to remarkable improvements thanks to the introduction of new devices, instruments, materials, and techniques, after earlier applications had not been sufficiently effective. Techniques involving combined approaches have been refined and modified. TDS methods have been modified through the introduction of sialendoscopy-assisted TDS in submandibular stones and a retropapillary approach for distal parotid sialolithiasis. Recent trends have revealed a potential for significant changes in therapeutic strategies for both major salivary glands. For the submandibular gland, ISWL has replaced ESWL and TDS to some extent. For parotid stones, ISWL and modifications of TDS have led to reduced use of ESWL and the combined transcutaneous–sialendoscopic approach. To illustrate these changes, we are here providing an updated treatment algorithm, including tried and tested techniques as well as promising new treatment modalities. Prognostic factors (e.g., the size or location of the stones), which are well recognized as having a strong impact on the prognosis, are taken into account and supplemented by additional factors associated with the new applications (e.g., the visibility or accessibility of the stones relative to the anatomy of the duct system).

Highlights

  • Sialolithiasis represents 40–60% and 70–85% of all obstructive diseases in the submandibular and parotid glands, respectively [1]

  • The size, location, mobility, and shape of the stone were recognized as prognostic factors influencing the treatment results [23] and have all been taken into account in the new treatment algorithms, except for the shape of the stone

  • Due to the options available with Intraductal shock-wave lithotripsy (ISWL) and further developments in combined surgical techniques, it was considered that the role of factors relating to the anatomy of the ductal system is more adequately covered by replacing the term “visible” with the term “accessible.” The use of this term is intended to emphasize the fact that, in view of recent developments— concerning ISWL—the accessibility of a stone in addition to its size is of paramount importance in comparison with all of the other prognostic factors mentioned in the literature

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Summary

Introduction

Sialolithiasis represents 40–60% and 70–85% of all obstructive diseases in the submandibular and parotid glands, respectively [1]. Good results were reported with a thulium laser [95] and in early publications with the use of excimer [85] or pulsed-dye lasers [86], these proved to be impractical and/or were too expensive It is not clear whether difficult sialolithiasis or stones in difficult locations were included in the latter studies [85,86]. Due to the options available with ISWL and further developments in combined surgical techniques, it was considered that the role of factors relating to the anatomy of the ductal system is more adequately covered by replacing the term “visible” with the term “accessible.” The use of this term is intended to emphasize the fact that, in view of recent developments— concerning ISWL—the accessibility of a stone in addition to its size is of paramount importance in comparison with all of the other prognostic factors mentioned in the literature.

Stones at the Papilla and in the Distal and Middle Duct
Stones in the Proximal to Hilar Duct System
Posthilar to Intraparenchymal Stones
Stones in the Papilla and Distal Excretory Duct
Stones in the Middle or Proximal Duct and Hilar Region
Hilar to Intraparenchymal Stones
Findings
Conclusions

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