Abstract

PurposeNo standardized treatment regimen exists for juvenile recurrent parotitis (JRP). The investigators hypothesized that irrigation with saline only without local anesthesia will be an effective and beneficial option.MethodsUsing a retrospective study design, a series of children with typical symptoms of JRP who were treated with at least one irrigation therapy were evaluated. This treatment consisted of irrigation of the affected gland with 3–10 ml saline solution without any type of anesthesia. The outcome variables were patient/parent satisfaction, frequency and duration of acute JRP episodes, and the need for antibiotics before and after irrigation therapy.ResultsThe case series was composed of six boys aged 3.3–7.7 years who experienced one to eight sessions of irrigation therapy. The period of follow-up was 9–64 months. We observed a total resolution of symptoms in two children and an improvement in the other four. No relevant side effects were seen.ConclusionOur results suggest that irrigation therapy is a reasonable, simple, and minimally invasive treatment alternative for JRP. In contrast to sialendoscopy or sialography, there is no need for general anesthesia or radiation exposure.

Highlights

  • Juvenile recurrent parotitis (JRP) is a disorder of unknown origin which affects less than 1% of children [1]

  • Only a few reports have been published about the successful use of irrigation either alone or in combination with topical antibiotics, or along with systemic steroids as a treatment for chronic sialadenitis in general

  • Antoniades and co-authors reported a larger case series of 82 patients with various types of chronic sialadenitis treated by intraductal injection of saline with or without penicillin G [10]

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Summary

Introduction

Juvenile recurrent parotitis (JRP) is a disorder of unknown origin which affects less than 1% of children [1]. Portions of this study were presented at: The 85th annual meeting of the German Society of Oto-Rhino-Laryngology, Head and Neck Surgery (Dortmund, Germany, 2014) and 5th International Salivary Gland Congress/1st Multidisciplinary Salivary Gland Society Meeting at the University of Pennsylvania (Philadelphia, USA, 2019); (first prize winner for best poster in the inflammatory diseases category) At this time, there is no general consensus about the most suitable treatment regimen for JRP [5]. We analyzed outcomes from patients with JRP who were treated by irrigation of the gland with saline solution using a simple flexible intravenous catheter inserted into the papilla of the duct. The child was asked to bite onto the cap of the Luer lock connector, which is situated orthogonally to the main direction of the catheter (Fig. 2) This held the catheter in place and allowed for easy removal of the stylet.

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25. Administration UFaD: FDA Drug Safety Communication
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