Abstract
The article deals with the burning question of treatment of hypertension in patients with ischemic heart disease. Hypertension is one of the major modifiable risk factors for stroke, heart failure, and ischemic heart disease. Arterial hypertension and ischemic heart disease are often comorbid conditions with common pathogenetic mechanisms. Because of the huge social significance of these diseases and their complications it is extremely important to find ways to improve efficacy of treatment of patients with these concomitant conditions. According to the clinical pharmacology data and the results of numerous clinical studies, dihydropyridine calcium antagonists turned out to be an effective treatment for hypertension in combination with ischemic heart disease. Through the example of calcium channel blockers, amlodipine in particular, the efficacy of this group of drugs for treating patients with hypertension and high risk for cardiovascular complications was demonstrated. Amlodipine exhibits antihypertensive, anti-anginal and antiatherosclerotic properties and is able to protect myocard. Moreover, amlodipine has a favourable safety profile, which preconditions its extensive use in clinical practice, in particular for the treatment of hypertension in combination with ischemic heart disease.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
