Abstract
H elicobacter pylori infection and nonsteroidal anti-inflammatory drugs (NSAIDs) have both been associated with increased risk for peptic-ulcer disease. Two recent studies explore the contribution of each, the interactions between them, and possible interventions to lessen risk for ulcers. In a double-blind, randomized, placebo-controlled trial, Chan and colleagues recruited NSAID-naive patients with positive H. pylori breath tests and a history of dyspepsia or peptic ulcers who required long-term NSAID therapy. Patients were randomized to receive omeprazole …
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