Abstract
Implication for health policy/practice/research/medical education: Transplantation is now a well-accepted therapy for end organ failure. However the recipients are required to take life-long immunosuppression to prevent rejection. This leads to immunosuppression associated morbidity in the form of viral/ fungal/ bacterial infections in addition to causing financial burden on the system. Over a long run these patients are at high risk to develop malignancies.In spite of all these efforts, the graft is lost over 7-10 years to chronic graftattrition/ rejection. The only answer to this problem is "Transplant tolerance" which means stable allograft function while maintaining third party immuneresponse intact in absence of rejections on no immunosuppression. Since last 60 years transplanters across the globe are in search of this "Mackenna's gold". The following editorial discusses how far have we progressed in our search for the promised land of "Transplant Tolerance."
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
