Abstract
Immunogenetics and Tissue Typing in ManThe antigenic polymorphism discussed in the first section of this review is maintained through the action of many genes at a number of different loci. Analysis of the mode of transmission and mechanisms of action of these genes constitutes a formidable problem.The availability of highly inbred mouse strains has permitted a formal genetic analysis of histocompatibility in that species, in which 15 independent loci have been positively identified and partially characterized.55 Of these, the H-2 locus and its associated antigenic specificities constitute the most thoroughly studied histocompatibility system in any species. The present . . .
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