Abstract
SummaryThe ability of 2 polyoma virus strains, 3049 and lp-D, to produce transplant immunity in adult hamsters against tumor cells induced by both strains was studied. The 3049 virus immunized hamsters against tumor cells produced by itself, but tended to enhance the growth of lp-D virus-induced tumor cells. On the other hand, the lp-D virus produced little or no immunity against its own tumor cell, but enhanced the growth of 3049 virus-induced cells. X-irradiated tumor cells induced by the 3049 virus, when given to adult hamsters, enhanced the growth of both 3049 and lp-D tumors. Possible explanations for these paradoxical results, based on the presence of at least 2 transplant antigens, were discussed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
