Abstract
We stand at the edge of a new frontier in health care. The Affordable Care Act-2010 has encouraged researchers and clinicians to work constructively and cooperatively toward maximizing convergent translational patient-centered, effectivenessfocused and evidence-based health care. While developing innovative molecular and cellular biology techniques to inform translational research, the field has validated the sophisticated comparative effectiveness research protocol in translational effectiveness aimed at defining and characterizing the best evidence base for translational convergent health care in general, and translational dental practice in particular. The salient principles and criteria for translational convergent biomedicine of the XXI century are discussed in this paper.
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