Abstract

Two patients with transitory benign plaques of the tongue have been benefited by the local use of a solution of penicillin. REPORT OF CASES Case 1.— M. K., a 22 year old white nurse, was seen with an eruption on the tongue of over three years' duration. The lesions came and went in rapid succession and were practically asymptomatic. Treatment in the past had included two roentgen ray treatments of 75 r each, which had cleared the tongue for eight to ten days, after which the disorder recurred. Examination showed discrete and confluent round slick pink patches with gray borders on the sides and dorsum of the tongue. Oral and dental hygiene was good. Bacteriologic studies showed the presence of a staphylococcus (facultative aerobe) and an anaerobic nonhemolytic streptococcus. She was given a solution containing 1,000 units of calcium penicillin per cubic centimeter of isotonic solution of sodium chloride to

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