Abstract
This is a case series of five adult patients obtained from the medical intensive care unit in a community teaching hospital between May 2019 through August 2020. These patients were each receiving dexmedetomidine infusion while on invasive mechanical ventilation leading to periods of asystole that resolved after stopping dexmedetomidine infusion in all five patients.
Highlights
Materials and methodsThis is a case series of five adult patients obtained from the medical intensive care unit in a community teaching hospital between May 2019 through August 2020
Dexmedetomidine is a highly selective central alpha 2 receptor agonist with favorable effects when used for sedation in mechanically ventilated patients.Dexmedetomidine decreases anxiety, and delirium by acting on the locus coeruleus and has the added benefit of having a narcotic sparing effect and has no respiratory suppression
The routine use of continued infusion of dexmedetomidine can lead to asystole if instigated by common vagal stimulation of the trachea during mechanical ventilation
Summary
This is a case series of five adult patients obtained from the medical intensive care unit in a community teaching hospital between May 2019 through August 2020. These patients were each receiving dexmedetomidine infusion while on invasive mechanical ventilation leading to periods of asystole that resolved after stopping dexmedetomidine infusion in all five patients
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More From: International Journal of Critical Care and Emergency Medicine
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