Abstract
Mutagenesis by C-to-U events specifically in either DNA strand assayed with ung uvrA defective Escherichia coli on a metabolically restrictive medium produces more glutamine tRNA suppressor mutations from U occurring in the non-transcribed DNA strand than from U in the transcribed (template) DNA strand. This bias is the reverse of what might be expected from transcriptional mutagenesis (mutation expression utilizing mutated RNA transcribed from damaged template strand DNA). The results and related ideas are discussed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
