Abstract
Superior cervical ganglia from 6-day and 4-week-old mice showed increased tyrosine hydroxylase activity when cultured for 48 h in media containing 5 or 15 times the normal potassium concentration. Increased sodium concentration had no such effect. These results suggest that depolarisation of adrenergic neurones may be important in the trans-synaptic regulation of enzyme activity in both adult and neonatal ganglia.
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