Abstract
A new capillary electrophoretic method for trace analysis of γ-cyclodextrin, γ-CD, in a sample of β-CD has been developed, building on our recent work in which the tetraphenylborate ion, Ph 4B −, was found to bind to γ-CD three orders of magnitude more strongly than to β-CD. The method involves measurement of the change of net electrophoretic mobility of Ph 4B − and its CD complexes in a background electrolyte containing a fixed concentration of β-CD. Good linearity was found between 1/Δ μ and 1/ C γ, where Δ μ is the difference in the mobility of Ph 4B − in the β-CD solution at a given and at zero concentration of γ-CD, and C γ the γ-CD concentration. The limit of detection for γ-CD in a β-CD sample was found to be 0.020% (w/w), and high precision and accuracy were obtained.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
