Towards Automatic Detection of Pneumothorax in Emergency Care with Deep Learning Using Multi-Source Chest X-ray Data

Coronavirus (COVID-19) is a fast-spreading virus-related disease. On 28 March 2022, Worldometer (COVID-19 live update) reported that there were about 482,338,923 COVID-19 cases and 6,149,387 fatalities worldwide. Moreover, there were about 416,884,712 recovered patients. The primary clinical mechanism currently utilized for COVID-19 identification is the Reverse Transcription–Polymerase Chain Reaction (RT-PCR). Hospitals only have small quantities of COVID-19 test kits available due to the daily increase in cases. As an alternative diagnosis possibility, an automatic detection system was implemented. A vigorous technique for the automatic COVID-19 identification is the deep learning approach. Chest X-ray (CXR) imaging is a modest tool that can be an alternate for diagnosing COVID-19-infected patients. With the use of deep learning, deep layer characteristics that are hidden from human sight may be observed using CXR imaging. One of the largest public databases, the “COVID-19 Radiography Database”, comprises 21,164 CXR images and was taken from Kaggle. To achieve the best accuracy in this work, data cleansing and the balanced dataset approach were applied. The primary goal of data cleansing is to remove duplicate CXR images from the database. The accuracy of three distinct pre-trained Convolutional Neural Networks (CNNs) was compared and then analyzed (Xception, InceptionV3, and MobileNetV2). Among other models, Xception achieved the best testing accuracy of 94.13% with plain lung CXR pictures. The Gabor filtering image enhancement approach was also employed to identify COVID-19. Only for the MobileNetV2 model did enhance CXR images perform significantly better for classification than plain lung CXR images. This study attempts to enhance the system’s accuracy to 100%, outperforming previous tests.

Fighting against <scp>COVID</scp>‐19: Innovations and applications

Chest X-ray (CXR) imaging is a standard and crucial examination method used for suspected cases of coronavirus disease (COVID-19). In profoundly affected or limited resource areas, CXR imaging is preferable owing to its availability, low cost, and rapid results. However, given the rapidly spreading nature of COVID-19, such tests could limit the efficiency of pandemic control and prevention. In response to this issue, artificial intelligence methods such as deep learning are promising options for automatic diagnosis because they have achieved state-of-the-art performance in the analysis of visual information and a wide range of medical images. This paper reviews and critically assesses the preprint and published reports between March and May 2020 for the diagnosis of COVID-19 via CXR images using convolutional neural networks and other deep learning architectures. Despite the encouraging results, there is an urgent need for public, comprehensive, and diverse datasets. Further investigations in terms of explainable and justifiable decisions are also required for more robust, transparent, and accurate predictions.

Infectious diseases pose a threat to human life and could affect the whole world in a very short time. Corona-2019 virus disease (COVID-19) is an example of such harmful diseases. COVID-19 is a pandemic of an emerging infectious disease, called coronavirus disease 2019 or COVID-19, caused by the coronavirus SARS-CoV-2, which first appeared in December 2019 in Wuhan, China, before spreading around the world on a very large scale. The continued rise in the number of positive COVID-19 cases has disrupted the health care system in many countries, creating a lot of stress for governing bodies around the world, hence the need for a rapid way to identify cases of this disease. Medical imaging is a widely accepted technique for early detection and diagnosis of the disease which includes different techniques such as Chest X-ray (CXR), Computed Tomography (CT) scan, etc. In this paper, we propose a methodology to investigate the potential of deep transfer learning in building a classifier to detect COVID-19 positive patients using CT scan and CXR images. Data augmentation technique is used to increase the size of the training dataset in order to solve overfitting and enhance generalization ability of the model. Our contribution consists of a comprehensive evaluation of a series of pre-trained deep neural networks: ResNet50, InceptionV3, VGGNet-19, and Xception, using data augmentation technique. The findings proved that deep learning is effective at detecting COVID-19 cases. From the results of the experiments it was found that by considering each modality separately, the VGGNet-19 model outperforms the other three models proposed by using the CT image dataset where it achieved 88.5% precision, 86% recall, 86.5% F1-score, and 87% accuracy while the refined Xception version gave the highest precision, recall, F1-score, and accuracy values which equal 98% using CXR images dataset. On the other hand, and by applying the average of the two modalities X-ray and CT, VGG-19 presents the best score which is 90.5% for the accuracy and the F1-score, 90.3% for the recall while the precision is 91.5%. These results enables to automatize the process of analyzing chest CT scans and X-ray images with high accuracy and can be used in cases where RT-PCR testing and materials are limited.

The chest X-ray examination is one of the most important methods for screening and diagnosing of many lung diseases. Diagnosis of pneumonia by chest X-ray is one of the common methods used by medical experts. However, the image quality of chest X-Ray has some defects, such as low contrast, overlapping organs and blurred boundary, which seriously affects detecting pneumonia in chest X-rays. Therefore, it has important medical value and application significance to construct a stable and accurate automatic detection model of pneumonia through a large number of chest X-ray images. In this paper, we propose a novel hybrid system for detecting pneumonia from chest X-Ray image: ACNN-RF, which is an adaptive median filter Convolutional Neural Network (CNN) recognition model based on Random forest (RF). Firstly, the improved adaptive median filtering is employed to remove noise in the chest X-ray image, which makes the image more easily recognized. Secondly, we establish the CNN architecture based on Dropout to extract deep activation features from each chest X-ray image. Finally, we employ the RF classifier based on GridSearchCV class as a classifier for deep activation features in CNN model. It not only avoids the phenomenon of over-fitting in data training, but also improves the accuracy of image classification. During our experiment, the public chest X-ray image dataset used in the experiment contains 5863 images, which comprises 4265 frontal-view X-ray images of 1574 unique patients. The average recognition rate of pneumonia is up to 97% by the proposed ACNN-RF. The experimental results show that the ACNN-RF identification system is more effective than the previous traditional image identification system.

Novel coronavirus disease (COVID-19) is an extremely contagious and quickly spreading coronavirus infestation. Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), which outbreak in 2002 and 2011, and the current COVID-19 pandemic are all from the same family of coronavirus. This work aims to classify COVID-19, SARS, and MERS chest X-ray (CXR) images using deep convolutional neural networks (CNNs). To the best of our knowledge, this classification scheme has never been investigated in the literature. A unique database was created, so-called QU-COVID-family, consisting of 423 COVID-19, 144 MERS, and 134 SARS CXR images. Besides, a robust COVID-19 recognition system was proposed to identify lung regions using a CNN segmentation model (U-Net), and then classify the segmented lung images as COVID-19, MERS, or SARS using a pre-trained CNN classifier. Furthermore, the Score-CAM visualization method was utilized to visualize classification output and understand the reasoning behind the decision of deep CNNs. Several deep learning classifiers were trained and tested; four outperforming algorithms were reported: SqueezeNet, ResNet18, InceptionV3, and DenseNet201. Original and preprocessed images were used individually and all together as the input(s) to the networks. Two recognition schemes were considered: plain CXR classification and segmented CXR classification. For plain CXRs, it was observed that InceptionV3 outperforms other networks with a 3-channel scheme and achieves sensitivities of 99.5%, 93.1%, and 97% for classifying COVID-19, MERS, and SARS images, respectively. In contrast, for segmented CXRs, InceptionV3 outperformed using the original CXR dataset and achieved sensitivities of 96.94%, 79.68%, and 90.26% for classifying COVID-19, MERS, and SARS images, respectively. The classification performance degrades with segmented CXRs compared to plain CXRs. However, the results are more reliable as the network learns from the main region of interest, avoiding irrelevant non-lung areas (heart, bones, or text), which was confirmed by the Score-CAM visualization. All networks showed high COVID-19 detection sensitivity (> 96%) with the segmented lung images. This indicates the unique radiographic signature of COVID-19 cases in the eyes of AI, which is often a challenging task for medical doctors.

since the global pandemic of COVID-19 has spread out, the use of Artificial Intelligence to analyze Chest X-Ray (CXR) image for COVID-19 diagnosis and patient treatment is becoming more important. This research hypothesized that using COVID19 radiographic changes in the X-Ray images. Artificial Intelligence (AI) systems may extract certain graphical elements regarding COVID-19 and offer a clinical diagnosis ahead of pathogenic test; therefore, saving vital time for disease prevention. Employing 2614 CXR radiographs from Kaggle data collection of verified COVID-19 cases and healthy persons, a new Convolutional Neural Network (CNN) model that is inspired by the Xception architecture was presented for the diagnosis of coronavirus pneumonia infected patients. The suggested technique reached an average validation accuracy of 0.99, precision of 0.95, recall of 0.92, and F1-score of 0. 95. Finally, such findings revealed that the Deep Learning (DL) technique has the potential to decrease frontline radiologists' stress, enhance early diagnosis, treatment, and isolation; therefore, aid in epidemic control. Index Terms— Chest X-ray images, Convolutional Neural Network, COVID-19, Detection.

Chest X-ray (CXR) images provide an effective modality for detecting COVID-19 infections. Nevertheless, the interpretation of CXR images is challenging and operator-dependent task. Several studies proposed the use of pretrained convolutional neural network (CNN) models to classify CXR images with the goal of detecting COVID-19 infections. In fact, the classification of CXR images using the pretrained CNN models is essentially performed using two approaches, namely the transfer learning approach and deep features extraction approach. This study aims to compare the performance of these two approaches to classify CXR images as COVID-19, pneumonia, and normal. Three pretrained CNN models, namely the AlexNet, VGG19, and ResNet50 CNN models, have been utilized. Furthermore, a balanced dataset of CXR images is used to perform the analysis, where this dataset includes 1,228 COVID-19 CXR images, 1,228 pneumonia CXR images, and 1,228 normal CXR images. For the three pretraiend CNN models, the deep features extraction approach achieved better classification results compared with the transfer learning approach. Moreover, the results show that the ResNet50 CNN model obtained the highest classification performance based on the transfer learning approach and the deep features extraction approach. The highest macro-averaged sensitivity, specificity, and F1 score values, which have been achieved using the deep features extraction approach and the ResNet50 CNN model, are equal to 93.7%, 96.9%, and 93.7%, respectively.

Background: Tuberculosis (TB) is a highly infectious disease with a high mortality rate if left untreated. Traditional diagnostic methods, like skin tests and sputum smear cultures, are unreliable and time-consuming. Artificial Intelligence (AI) and Deep Learning (DL) can revolutionize healthcare by improving disease diagnosis. This study developed an AI system using Convolutional Neural Network (CNN) to detect TB by analyzing digitalized chest X-ray (CXR) images, which can significantly improve the accuracy and speed of TB diagnosis, leading to better patient outcomes. Methods: A CNN model was developed; it uses a methodology that cuts the edges for analyzing the CXR images for detecting the tuberculosis symptoms in it. A database of chest X-ray images for tuberculosis which was gathered by a team of researchers was used to train the model for detecting tuberculosis. Result: This study uses deep learning to predict tuberculosis using a CNN model with 97% accuracy on CXR images. The patient can be informed about the severity of tuberculosis by the model, which analyzes and checks the tuberculosis symptoms in their CXR image. Conclusion: In summary, the advancement of AI and DL has brought about a significant transformation in the healthcare industry, particularly in the detection, diagnosis, and treatment of diseases. The use of AI and DL in tuberculosis diagnosis has been explored in this study through the development of a CNN model that was trained on chest X-ray images. AI and DL can significantly reduce tuberculosis mortality rates by aiding in early detection.

A deep learning and grad-CAM based color visualization approach for fast detection of COVID-19 cases using chest X-ray and CT-Scan images

Uncertainty-aware convolutional neural network for COVID-19 X-ray images classification

Pneumonia is one of the most dangerous respiratory diseases and could be life-threatening if not promptly diagnosed and treated. In addition, pneumonia is an infectious disease, and missing a case poses a significant risk to the community. Conventionally, doctors rely on chest X-ray (CXR) images to examine the lungs and detect abnormalities associated with pneumonia. The development of artificial intelligence (AI), especially deep learning (DL) algorithms, can assist doctors in diagnosing the disease more quickly and accurately. This study proposes a hybrid DL model that combines two convolutional neural networks (CNNs), VGG16 and VGG19, with an attention mechanism to enhance pneumonia detection from CXR images. By integrating the lightweight structure of VGG16 with the deeper feature extraction of VGG19 and directing focus to key pathological regions through attention, the model achieves improved diagnostic performance. Evaluated on a public pediatric CXR dataset, the proposed model outperforms VGG16, VGG19, DenseNet121, and InceptionV3 in all major metrics: 89.10% accuracy, 86.42% precision, 91.82% F1-score, and 97.95% recall. The high recall rate is particularly significant in minimizing false negatives, which is critical in clinical contexts to prevent missed pneumonia cases. Despite having the highest parameter count among the compared models, it maintains a fast inference time of 33.48 ms per image, supporting real-time clinical application.

COVID-19 has engulfed over 200 nations through human-to-human transmission, either directly or indirectly. Reverse Transcription-polymerase Chain Reaction (RT-PCR) has been endorsed as a standard COVID-19 diagnostic procedure but has caveats such as low sensitivity, the need for a skilled workforce, and is time-consuming. Coronaviruses show significant manifestation in Chest X-Ray (CX-Ray) images and, thus, can be a viable option for an alternate COVID-19 diagnostic strategy. An automatic COVID-19 detection system can be developed to detect the disease, thus reducing strain on the healthcare system. This paper discusses a real-time Convolutional Neural Network (CNN)based system for COVID-19 illness prediction from CX-Ray images on the cloud. The implemented CNN model displays exemplary results, with training accuracy being 99.94% and validation accuracy reaching 98.81%. The confusion matrix was utilized to assess the models' outcome and achieved 99% precision, 98% recall, 99% F1 score, 100% training area under the curve (AUC) and 98.3% validation AUC. The same CX-Ray dataset was also employed to predict the COVID-19 disease with deep Convolution Neural Networks (DCNN), such as ResNet50, VGG19, InceptonV3, and Xception. The prediction outcome demonstrated that the present CNN was more capable than the DCNN models. The efficient CNN model was deployed to the Platform as a Service (PaaS) cloud.

A lightweight CNN-based network on COVID-19 detection using X-ray and CT images

The coronavirus (COVID-19) is a major global disaster of humankind, in the 21st century. COVID-19 initiates breathing infection, including pneumonia, common cold, sneezing, and coughing. Initial detection becomes crucial, to classify the virus and limit its spread. COVID-19 infection is similar to other types of pneumonia, and it may result in severe pneumonia, with bundles of illness onsets. This research is focused on identifying people affected by COVID-19 at a very early stage, through chest X-ray images. Chest X-ray classification is a beneficial method in the identification, follow up, and evaluation of treatment efficiency, for people with pneumonia. This research, also, considered chest X-ray classification as a basic method to evaluate the existence of lung irregularities in symptomatic patients, alleged for COVID-19 disease. The aim of this research is to classify COVID-19 samples from normal chest X-ray images and pneumonia-affected chest X-ray images of people, for early identification of the disease. This research will help people in diagnosing individuals for viruses and insisting that people receive proper treatment as well as preventive action, to stop the spread of the virus. To provide accurate classification of disease in patients’ chest X-ray images, this research proposed a novel classification model, named 2dCNN-BiCuDNNLSTM, which combines two-dimensional Convolutional Neural Network (CNN) and a Bidirectional CUDA Deep Neural Network Long Short-Term Memory (BiCuDNNLSTM). Deep learning is known for identifying the patterns in available data that will be helpful in accurate classification of disease. The proposed model (2dCNN and BiCuDNNLSTM layers, with proper hyperparameters) can differentiate normal chest X-rays from viral pneumonia and COVID-19 ones, with high accuracy. A total of 6863 X-ray images (JPEG) (1000 COVID-19 patients, 3863 normal cases, and 2000 pneumonia patients) have been engaged, to examine the achievement of the suggested neural network; 80% of the images dataset for every group is received for proposed model training, 10% is accepted for validation, and 10% is accepted for testing. It is observed that the proposed model acquires the towering classification accuracy of 93%. The proposed network is used for predictive analysis, to prompt people regarding the risk of early detection of COVID-19. X-ray images help to classify people with COVID-19 variants and to indicate the severity of disease in the future. This study demonstrates the effectiveness of the proposed CUDA-enabled hybrid deep learning models, to classify the X-ray image data, with a high accuracy of detecting COVID-19. It reveals that the proposed model can be applicable in numerous virus classifications. The chest X-ray classification is a commonly available and reasonable approach, for diagnosing people with lower respiratory signs or suspected COVID-19. Therefore, it is demonstrated that the proposed model has an efficient and promising accomplishment for classifying COVID-19 through X-ray images. The proposed hybrid model can, efficiently, preserve the comprehensive characteristic facts of the image data, for more exceptional concluding classification results than an individual neural network.