Abstract
At a time when diagnostic bacteriological testing procedures have become more complex and their associated costs are steadily increasing, the expected benefits of Total laboratory automation (TLA) cannot just be a simple transposition of the traditional manual procedures used to process clinical specimens. In contrast, automation should drive a fundamental change in the laboratory workflow and prompt users to reconsider all the approaches currently used in the diagnostic work-up including the accurate identification of pathogens and the antimicrobial susceptibility testing methods. This review describes the impact of TLA in the laboratory efficiency improvement, as well as a new fully automated solution for AST by disk diffusion testing, and summarizes the evidence that implementing these methods can impact clinical outcomes.
Highlights
The early 19th century was characterized by the development of a large number of industry plants
Clinical microbiology laboratories are nowadays confronted with many different challenges including the needs: i) to enhance efficiency, ii) to deliver earlier results, iii) to comply with the increasingly demanding accreditation requirements, and iv) to meet the challenges raised by the growing number of multidrug resistant organisms
In addition to the measurable indicators exposed in the previous chapters, we considered the implementation of a fully automated solution for the antimicrobial susceptibility testing as one of the major indicators of success for our automation project
Summary
The early 19th century was characterized by the development of a large number of industry plants. The assessment and interpretation of culture media plates using digital images are still performed by the technologists who define which colonies of interest have to be isolated and further processed for identification and AST.
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