Abstract
To evaluate serial generation of microparticles (MPs) after laparoscopic stripping or CO2 laser vaporization in the surgical treatment of patients with ovarian endometrioma (OE). A prospective, randomized, blinded, pilot study (Canadian Task Force classification I). Tertiary care university hospital from December 2014 to July 2016. Thirty women with unilateral OE undergoing laparoscopic surgery. Patients were randomly selected to undergo either CO2 laser vaporization (L group) or laparoscopic stripping (S group) of OE. Blood samples were collected before surgery and at 2 hours, 24 hours, 1 month, and 3 months after surgery. An MP generation curve after OE surgery was created. MP generation was greater in the S group than in the L group at all time points evaluated. The MP generation curve showed a significantly higher area under the curve after excisional surgery (p <.05). The higher MP levels in the S group suggest an increased inflammation and procoagulant response after this procedure.
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