iScience | VOL. 25
Read

ToPP: Tumor online prognostic analysis platform for prognostic feature selection and clinical patient subgroup selection.

Publication Date May 20, 2022

Abstract

Patients with cancer with different molecular characterization and subtypes result in different response to anticancer therapeutics and survival. To identify features that are associated with prognosis is essential to precision medicine by providing clues for target identification, drug discovery. Here, we developed a tumor online prognostic analysis platform (ToPP) which integrated eight multi-omics features and clinical data from 68 cancer projects. It provides multiple approaches for customized prognostic studies, including 1) Prognostic analysis based on multi-omics features and clinical characteristics; 2) Automatic construction of prognostic model; 3) Pancancer prognostic analysis in multi-omics data; 4) Explore the impact of different levels of feature combinations on patient prognosis; 5) More sophisticated prognostic analysis according to regulatory network. ToPP provides a comprehensive source and easy-to-use interface for tumor prognosis research, with one-stop service of multi-omics, subtyping, and online prognostic modeling. The web server is freely available at http://www.biostatistics.online/topp/index.php.

Concepts
Powered ByUnsilo

Multi-omics Data
Multi-omics Features
Prognostic Analysis
Impact Of Different Levels
Prognostic Model
Web Server
Molecular Characterization
Patient Prognosis
Drug Discovery
Prognostic Subgroup

Introducing Weekly Round-ups!Beta

Powered by R DiscoveryR Discovery

Round-ups are the summaries of handpicked papers around trending topics published every week. These would enable you to scan through a collection of papers and decide if the paper is relevant to you before actually investing time into reading it.

Climate change Research Articles published between Jun 13, 2022 to Jun 19, 2022

R DiscoveryJun 20, 2022
R DiscoveryArticles Included:  5

Understanding the effects of the snow ratio on glacier mass balance under variable climatic conditions is crucial for predicting how glaciers will res...

Read More

Good health Research Articles published between Jun 13, 2022 to Jun 19, 2022

R DiscoveryJun 20, 2022
R DiscoveryArticles Included:  5

In West Africa, the various types of diabetes according to WHO or the American Diabetes Association (ADA) are endemic; a particular type referred to a...

Read More

Gender Equality Research Articles published between Jun 13, 2022 to Jun 19, 2022

R DiscoveryJun 20, 2022
R DiscoveryArticles Included:  5

This study aims to evaluate changes in the presence of women on Spanish boards after the Unified Good Governance Code of Listed Companies (2006) and t...

Read More

Coronavirus Pandemic

You can also read COVID related content on R COVID-19

R ProductsCOVID-19

ONE PROBLEM . ONE PURPOSE . ONE PLACE

Creating the world’s largest AI-driven & human-curated collection of research, news, expert recommendations and educational resources on COVID-19

COVID-19 Dashboard