Abstract
Background and Objectives: Preterm labour complicates 5-10% of pregnancies and is a leading causeof neonatal morbidity and mortality worldwide. It is a major public health problem in terms of loss of life,long-term disability (cerebral palsy, blindness, deafness, chronic lung disease) and health care costs both inthe developing and the developed world.There is need for tocolytic therapy to reduce perinatal mortality and morbidity by delaying delivery at leastfor 48 hours to allow time for therapeutic effects of corticosteroidsMethodology : This study was undertaken at Sri Siddhartha medical college and hospital research centretumakuru between October 2017 to October 2019.76 Antenatal cases with gestational age 28weeks-37weeks as per the inclusion and exclusion criteria’s whowere admitted and clinically diagnosed as preterm labour were selected . The selected patients were treatedwith Nitro-glycerine patchResults : Success rate for acute tocolysis was 88.2%.Mean prolongation of pregnancy was 14.46 days andmean birth weight of babies was 2.19 kilograms. Most common side effect with Nitroglycerine patch washeadache (5.3%).Conclusion: Nitroglycerine patch is effective in suppression of preterm labor as short term tocolytic inprolongation of pregnancy. Nitroglycerine is well tolerated and safe for the mother and fetus with minorside effects
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