To compare the role of Gd-EOB-DTPA dynamic contrast-enhanced MRI with multi-detector row computed tomography (MDCT) in patients with focal liver lesions

Abstract

Objective To compare the role of Gd-EOB-DTPA dynamic contrast-enhanced mag- netic resonance imaging （DCE-MRI） with multi- detector row computed tomography （MDCT）, and to determine the sensitivity, specificity and accuracy in foca! hepatic lesions. Methods A retrospective a- nalysis was conducted on 32 patients with focal hepatic lesions who had undergone MRI and MDCT examinations. These patients were divided into two groups： the CT group and the MRI group. The results were analysed using receiver operating characteristic （ROC） curves. Result There were 185 focal hepatic lesions. The sensitivity, specificity and the area under the ROC curve （AUC） were 86.5%, 90.9%, 0. 855, respectively for the MRI group and they were significantly higher than the CT group （63.6%, 54.5%, 0. 532）. For detection of lesions 〈1 cm, the sensitivity, specificity and the area under the ROC curve （AUC） for the MRI group were 90%, 86.6%, 0. 886, respectively, which were also significantly higher than the CT group （50.5%, 45.5%, 0. 500）. When combined with pathological findings and follow-up, the diagnostic accuracy was 40.6% using Gd-EOB-DTPA DCE- MRI. Conclusion Gd-EOB-DTPA DCE-MRI has a higher detection rate, better accuracy and diagnostic value for focal liver lesions （〈1 cm） than MDCT. Key words: Gd-EOB-DTPA; Dynamic contrast-enhanced magnetic resonance imaging; Focal hepatic lesions