Abstract
Aim: To assess the maternal anaemia, intra-uterian growth restriction and neonatal outcome.
 Materials and methods: a prospective, observational study conducted in Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College and Hospital, Bhagalpur, Bihar India. A total of 240 consecutive clinically suspected cases of IUGR with singleton pregnancies at 34-40 weeks of gestation were included in the study. Their socio-demographic profile and hemoglobin levels were recorded. A descriptive analysis of the data was performed.
 Results: Of 240 study subjects with IUGR at 34-40 weeks, 70.4% were anaemic, (48.8% had mild, 20.8% had moderate, 0.83 % had severe anaemia) while 29.6% were not anaemic. Significantly, the ratio of anaemic to non anaemic in antenatal IUGR pregnancies was 2.48:1. A birth weight of less than 2.5 kgs was recorded in 84% of pregnancies with moderate anaemia and 83.8% pregnancies with mild anaemia. Out of the 240 clinically diagnosed cases of IUGR 71.25% (n=171) were from the rural background and 28.75% (n=69) were urban area.
 Conclusion: Mild to severe anaemia in IUGR may increase the chances of low birth weight and adverse neonatal outcomes but larger studies with standardized definitions and measurements of exposure outcomes to bring about uniformity are required to determine an accurate assessment of association between low maternal hemoglobin and IUGR
Highlights
Anemia is characterized as a “low level of hemoglobin in the blood, as evidenced by a reduced quality or quantity of red blood cells,” which impairs oxygen delivery to the tissues
A birth weight of less than 2.5 kgs was recorded in 84% of pregnancies with moderate anaemia and 83.8% pregnancies with mild anaemia
The aim of this study was to decipher any significant association between maternal anaemia in clinically diagnosed IUGR pregnancies and neonatal outcomes
Summary
Anemia is characterized as a “low level of hemoglobin in the blood, as evidenced by a reduced quality or quantity of red blood cells,” which impairs oxygen delivery to the tissues. Plasma volume expands to facilitate uteroplacental circulation, and proper expansion has been associated with better pregnancy outcomes.[4] With the plasma volume increase, the hemoglobin concentration falls until around the late second to early third trimester, increases slightly around wk 30, when production of RBC mass catches up.[5,6] The estimated hemoglobin reduction from prepregnancy to mid-pregnancy is ~15 g/L.7. For this reason, early pregnancy measures of hemoglobin may most accurately reflect the mother’s prepregnancy hemoglobin levels. Decision regarding delivery was taken in between 36-38 weeks depending on certain jeopardy of fetoplacental unit with
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