Abstract
Marbling score (MS) is the major qualitative trait that affects carcass quality in beef cattle. In this study, we examined the association between genetic polymorphisms of the titin-cap gene ( TCAP) and carcass traits in Korean native cattle (also known as Hanwoo). By direct DNA sequencing in 24 unrelated Korean cattle, we identified five sequence variants in 1.2 kb of TCAP. Among them, four common polymorphic sites were selected for genotyping in the beef cattle ( n = 437). Pair-wise linkage analysis with four polymorphisms showed strong linkage disequilibrium (LD), and three major haplotypes (freq. > 0.1) were constructed. Statistical analysis revealed that polymorphisms in intron1 ( g.346G > A) and exon2 ( g.592-597CTGCAG[ Leu-Gln] insdel) showed significant association with marbling score ( P cor. = 0.003 and 0.02, respectively). One haplotype, ht2[ C-G-G-del], also showed significant association with MS ( P cor. = 0.0004). Our findings suggest that polymorphisms in TCAP might be among the important genetic factors involved in carcass quality in beef cattle.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
