Abstract
Titanium is used in orthopedic and orthodontic implants because it has good corrosion resistance and excellent biocompatibility. Thus, studies seek to obtain a coating to improve the adhesion between the bone and the implant, by modifying the metal’s surface. The objective of this work was to biomimetically coat C.P. Ti with hydroxyapatite doped with silver nitrate, a component with antimicrobial properties, coating the metallic-ceramic composite with a polycaprolactone polymer film, which is known by generate improved implant-tissue interaction, and reducing postoperative complications from bacterial infections. The characterization of the material demonstrated the existence of the coating overall surface of the metallic substrate. The results obtained from the bacterial culture tests with Staphylococcus aureus showed that nitrate was effective in reducing the amount of live bacteria present in the supernatant, as well as those adhered to the surface of the material. In addition, the polymeric coating did not prevent the release of the bactericidal agent, not interfering in the effect there.
Highlights
Alterations in the functioning of cells, tissues or organs, inflammations affect millions of people around the world
The microstructural characterization of Ti sample coated only with hydroxyapatite (Ti+HA)+AgNO3 and Ti+HA+AgNO3+PCL proves the formation of a coating on the surface of the metallic substrate
The results from the X-ray diffraction analysis (XRD) analysis confirm the typical peaks of α phase, hydroxyapatite, silver and PCL
Summary
Alterations in the functioning of cells, tissues or organs (degenerative diseases), inflammations affect millions of people around the world. With this motivation, the search for new technologies that aim to improve and optimize products and processes is becoming progressively constant. The search for materials that allow the substitution of tissue and bones has increased significantly in the last few years[1,2,3,4]. Studies on the application of biomaterials of natural or synthetic origin have been gaining more space in biomedicine, as they allow the substitution or improvement of tissues, organs and body functions[5,6]. Ti) and its alloys have broad application in this area because of their high degree of resistance to corrosion in bodily fluids, as well as their low modulus of elasticity and characteristics as biocompatible materials[4,7,8,9]
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