Abstract
Tissue engineering offers the possibility to overcome limitations of current management for postprostatectomy incontinence and ED. Developed in recent years biotechnological feasibility of mesenchymal stem cell isolation, in vitro cultivation and implantation became the basis for new cell-based therapies oriented to induce regeneration of adult tissue. The perspective to offer patients suffering from post-prostatectomy incontinence or erectile dysfunction minimal invasive one-time procedure utilizing autologous stem cell transplantation is desired management.
Highlights
Prostatectomy is recommended choice of treatment for localized disease while in advanced cases the indications for surgery are gradually extending [1]
In light of the postulated MSC involvement in the development of androgen-independent prostate cancer, the utilization of this cell population should be only limited to patients who do not pose a risk of recurrence [65]
Tissue engineering has an unquestionable potential to improve the current management of postprostatectomy stress incontinence and erectile dysfunction
Summary
Tissue engineering offers the possibility to overcome limitations of current management for postprostatectomy incontinence and ED. Developed in recent years biotechnological feasibility of mesenchymal stem cell isolation, in vitro cultivation and implantation became the basis for new cell-based therapies oriented to induce regeneration of adult tissue. The perspective to offer patients suffering from post-prostatectomy incontinence or erectile dysfunction minimal invasive one-time procedure utilizing autologous stem cell transplantation is desired management
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