Abstract
Uveitis is a group of sight-threatening intraocular inflammatory diseases responsible for 5% to 20% of legal blindness in developed countries. 1 Durrani O.M. Meads C.A. Murray P.I. Uveitis: a potentially blinding disease. Ophthalmologica. 2004; 218: 223-236 Crossref PubMed Scopus (211) Google Scholar Timely control of inflammation is essential to prevent serious complications, and corticosteroid therapy is the mainstay of treatment for noninfectious uveitis. However, long-term exposure to corticosteroids has undesirable ocular and systemic side effects. 2 Jabs D.A. Rosenbaum J.T. Foster C.S. et al. Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel. Am J Ophthalmol. 2000; 130: 492-513 Abstract Full Text Full Text PDF PubMed Scopus (717) Google Scholar Among the available corticosteroid-sparing treatment options, the antimetabolites methotrexate and mycophenolate mofetil (MMF) are used commonly.
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