Abstract
For about ten years, it has been debated whether in principle it is possible to detect 1O 2 located within the cell membrane by performing experiments with cell suspensions or even in tissue. In this paper we present our investigations on photosensitized red-cell ghost suspensions (RCGSs) and our strategy for the detection of luminescence of singlet oxygen ( 1O 2) from the inside of the cell membrane. Using a very sensitive apparatus for time-resolved 1O 2 detection, a very promising sensitizer and an adequate experimental strategy, a very small amount of the detected luminescence indeed can be attributed to 1O 2 from the inside of the ghost membrane.
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