Three-month functional outcome predictors of systemic thrombolytic therapy in cerebral infarction

Abstract

The article analyzes the clinical, laboratory and neuroimaging predictors of a three-month functional outcome of systemic thrombolytic therapy in patients with cerebral infarction is presented. Recently, techniques for the diagnosis and treatment of cerebral infarction have been actively developed, which has led to a decrease in mortality and a significant improvement in the functional outcome in some patients. The therapeutic response to ongoing therapy cannot be accurately predicted prior to its initiation, which makes it difficult to make the right decision regarding treatment tactics. The main focus is on the search and evaluation of the degree of determination in the outcome of thrombolytic therapy of the most significant predictors, as well as their mutual potentiation. Identification of factors associated with an unfavorable outcome of systemic thrombolysis can contribute to a safer, more effective and more widespread use of this treatment method in the shortest possible time.