Abstract
In stable preterm infants (1000-1500g), three-hourly feeding can be followed safely. In infants < 1000g, there is insufficient evidence to advise on an optimal feeding interval, although a 2-h interval might be preferable.Prospero Registration Number: CRD42021246568. • Most of the units follow two-hourly feeding schedules without any evidence. • Recent trials suggest that the three hourly feeding schedules can be safely followed in stable preterm infants. • Low certainty evidence suggests that three-hourly feeding is safe in stable preterm infants (1000-1500 grams). •In infants with birthweight <1000 grams, two-hourly feeding may be considered as it was associated with a shorter time to full feeds in subgroup analysis.
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