ThP2.10 - Echocardiographic changes of left ventricular function in coronary artery bypass graft patients - A prospective study with meta-analysis

Abstract

Abstract Coronary artery bypass graft (CABG) improves left ventricular function and reverses adverse remodelling. This has resulted in improved survival rates and decreased the incidence of cardiac events. Systematic review identified the Echocardiographic (ECHO) indices followed by CABG from the published data. The second part of this study compares the ECHO index of the patients, who had CABG. Results Overall, 191 citations were identified from the initial search, of which 43 studies were retrieved. Later, 8 studies included in the review and 6 were subjected to meta-analysis. There was a change in E/A Ratio (MD = -0.33; 95% CI = -0.42 to -0.25), Peak A-Wave (MD = 0.57; 95% C.I = 0.20 to 0.94), and E/E’ Ratio (MD = -3.80; 95% CI = -4.87 to -2.73), Peak E-Wave (MD = 0.26; 95% CI = -0.08 to 0.60), Left ventricular ejection fraction (LVEF) (MD = -0.43; 95% CI = -1.79 to 0.93), diastolic dimension (MD = 0.12; 95% CI = -0.00 to 0.23). However, There was no change in systolic dimension (MD = 0.10; 95% CI = -0.04 to 0.24) among CABG cases. The prospective study includes 30 CABG cases. Of these, 23 (76.7%) males and 7 (23.3%) females with mean age was 62.12 + 8.16. There was a change (p <0.05) LVEF, peak systolic gradient (PSG) from pre operative to six months after CABG. Conclusion In spite the changes in E/A Ratio, Peak A-Wave, E/E’ Ratio, LVEF and PSG are the most important echocardiographic indices associated with CABG.