Abstract
Background Wall shear stress (WSS) may be associated with the onset and development of aortopathy in the presence of bicuspid aortic valve (BAV) [Michelena, JAMA (2011)]. The use of ‘aortic atlases’ of 3D WSS vectors allows for systematic analysis of WSS differences between large patient cohorts. In this study, a comparison is performed between WSS atlases of BAV patients, BAV patients with aortic dilation, patients with BAV stenosis, and healthy controls with tricuspid valves. The aim is to test the hypothesis that WSS atlases can identify regions of significantly altered WSS that are associated with different expression of BAV and aortopathy.
Highlights
Wall shear stress (WSS) may be associated with the onset and development of aortopathy in the presence of bicuspid aortic valve (BAV) [Michelena, JAMA (2011)]
The use of ‘aortic atlases’ of 3D WSS vectors allows for systematic analysis of WSS differences between large patient cohorts
A comparison is performed between WSS atlases of BAV patients, BAV patients with aortic dilation, patients with BAV stenosis, and healthy controls with tricuspid valves
Summary
Thoracic aortic wall shear stress atlases in patients with bicuspid aortic valves Pim van Ooij1*, Wouter V Potters, Aart J Nederveen, Jeremy D Collins, James C Carr, SC Malaisrie, Michael Markl, Alex J Barker. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. 16-19 January 2014
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