Abstract
On the example of tetraantraquinoporphyrazines—potential photosensitizers for photodynamic therapy, thermodynamic approach to the choice of exogenous transport system was demonstrated. By means of isothermal titration calorimetry and electron absorption spectroscopy, the state of TAP in aqueous solutions was studied. The possibility of aggregation equilibrium displacement due to the pyridine adding was evaluated.
Highlights
Metal complexes of tetraantraquinoporphyrazines (TAP) are perspective substances for practical use
That’s why information about complex formation between TAP metal complexes and electron-donor ligands is necessary for the design of transport system
UV-VIS spectrum of HOAlTAP(COONa)4 is shown on Figure 2
Summary
Metal complexes of tetraantraquinoporphyrazines (TAP) are perspective substances for practical use. All practically useful properties of TAP depend from tendency of TAP to aggregate in solutions [2]. That’s why it is necessary to establish the influence of peripheral substitute’s nature to TAP’s aggregation tendency [3]. Investigations devoted to revelation of regulation mechanism for TAP state in solutions are very actual. It can be the complex formation with neutral molecular ligands. The widening of aromatic system from porphyrazines to tetraantraquinoporphyrazines causes intensification of hydrophobic behavior of macroheterocycles and increases the tendency of macrocycles to self-aggregation [4]. That’s why information about complex formation between TAP metal complexes and electron-donor ligands is necessary for the design of transport system
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
