THERAPEUTIC STUDIES IN HYPERTHYROIDISM

Abstract

Article1 August 1941THERAPEUTIC STUDIES IN HYPERTHYROIDISMPAUL STARR, M.D., HERMAN POMERENZE, M.D.PAUL STARR, M.D.Search for more papers by this author, HERMAN POMERENZE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-15-2-226 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor several years attempts to suppress hyperthyroidism by various medicaments have been carried out in our clinic. The rationale of this project is furnished by the occurrence of spontaneous remissions occasionally observed in this disease and the physiological demonstration of a chalone type of mechanism in other endocrine relationships. Of the latter, pituitary suppression by estrogens, inhibition of lactation by androgens, and estrogen neutralization by progestin, may be mentioned. It would seem probable, therefore, that a physiological control of the over-active thyroid would be possible if a condition or substance acting as a chalone for the thyroid could be discovered....References STARR P: Clinical studies with thyrotropic pituitary hormone, Proc. Soc. Exper. Biol. and Med., 1935, xxxiii, 462-464. CrossrefGoogle Scholar STARRPATTON PH: Studies of variations in individual human response to thyrotropic hormone preparations, Ann. Trans. Am. Assoc. for the Study of Goiter (in press), West. Jr. Surg. Google Scholar STARRPATTON PH: Observations of remissions in hyperthyroidism induced by pregnancy urine extract, ANN. INT. MED., 1935, viii, 825-833. Google Scholar KUNDE MM: Studies on metabolism: experimental hyperthyroidism, Am. Jr. Physiol., 1927, lxxxii, 195-215. CrossrefGoogle Scholar KUSCHINSKY G: Über die Bedingungen der Sekretion des Thyreotropen Hormons der Hypophyse, Arch. f. exper. Path. u. Pharmakol., 1933, clxx, 510-533. CrossrefGoogle Scholar STARR P: Course of hyperthyroidism under iodine medication, Arch. Int. Med., 1927, xxxix, 520-535. CrossrefGoogle Scholar LEVY SIMPSON S: Value of testosterone propionate in hyperthyroidism, Postgrad. Med. Jr., 1938, xiv, 144-146. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication August 5, 1940.From the Department of Medicine, Northwestern University Medical School, Chicago. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDiseases of the Thyroid Gland 1 August 1941Volume 15, Issue 2Page: 226-243KeywordsAndrogensEstrogensHyperthyroidismLactationThyroid ePublished: 1 December 2008 Issue Published: 1 August 1941 PDF downloadLoading ...