Abstract
Objective To evaluate the clinical efficacy of compound matrine injection combined with fentanyl transdermal patch in the treatment of elderly patients with advanced gastric cancer. Methods A total of 100 elderly patients with advanced gastric cancer were enrolled in this study.All patients were randomly divided into the observation group(n=50)given compound matrine injection plus Fentanyl transdermal patch and the control group given fentanyl transdermal patch alone(n=50). The analgesic efficacy, quality of life and adverse reaction were evaluated and compared between the two groups. Results The analgesic efficacy was significantly higher in the observation group[76%(38/50)]than in the control group[(44%), (χ2=4.46, P 0.05). Conclusions Compound matrine injection plus Fentanyl transdermal patch are safe and effective in the treatment of carcinoma pain in elderly patients with advanced gastric cancer. Key words: Matrine; Fentanyl; Advanced gastric cancer; Carcinoma pain
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