Abstract
Objective To compare the efficacy and safety of gatifloxacin with ciprofloxacin for the treatment of pa-tients with acute bacterial exacerbations of chronic bronchitis (ABECB) in short course therapy. Methods Seventy - four cases with ABECB were randomly divided into treatment groups (gatifloxacin group) and control group (ciprofloxacin group) ,with 37 cases in each group. The efficacy and safety tithe two groups were investigated. Results The effective rate and bacteria eradication rate were 91.9% and 89.2% respectively in gatifloxacin group and 78.4% and 75.7% respective-ly in ciprofloxacin group, with significant between them (P < 0. 05). Conclusions Gatifloxacin is a broad - spectrum and safe antibiotic and has significant effect in short course therapy for the treatment of acute bacterial exacerbations of chronic bronchitis, and can be taken as the first choice drug on this disease. Key words: Gatifloxacin; Ciprofloxacin; Acute bacterial exacerbations of chronic bronchitis; Short - course therapy
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