Abstract

The metabolome is mentioned to small molecules inside the biological sample. The metabolome includes endogenous metabolites such as natural compounds such as nucleic acids, amino acids, vitamins, fatty acids, sugars, and exogenous compounds such as food additives, environmental toxicants, drugs xenobiotics. Human disease is induced by external factors e.g., pathogens or internal dysfunctions e.g: hypersensitivity, immunity disorders, autoimmune disorders, immunodeficiency, and allergy. There are 6 different types of human diseases: human acquired disease, human acute disease, human chronic disease, human congenital disease, human genetic disease, and incurable human disease. Human acute disease is appears suddenly and persists for a short human time. Human acute diseases such as influenza virus and the disease symptoms include fever. Human chronic diseases remain for 1 year or more and need continuing medical precaution or limit activities of human dailydaily human life activities. Human chronic diseases include heart diseases, cancers, and diabetes that cause human death or disability. Human congenital disease can be developed in the fetal growth stage or from the parents' genetic transfer. Genetic disease is a human health problem induced via one or more defects in the genome. The genetic disease is induced via one or more defects in the genome. In conclusion, the metabolome plays an important role in the therapeutic basis of all the above mentioned human diseases.

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