Abstract
A biophysical model is proposed for the simulation of the experimentally observed calcium action potential at the squid giant synapse. It is observed that while Ca activation at the synapse is responsible for the generation of the upstroke of the action potential, a repolarizing process needs to be invoked to simulate the plateau termination and other long-time effects. Out of the likely candidates, the Ca-activated K current has been chosen as the most plausible repolarizing process. The model can reproduce all the observed features of calcium action potential excepting its behaviour after repetitive stimulation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
