Abstract
Image-guidance for frame-based stereotaxis is facilitated by incorporating three to four N-localizers or Sturm-Pastyr localizers into a stereotactic frame. An extant frame that incorporates only two N-localizers violates the fundamental principle of the N-localizer, which requires three non-colinear points to define a plane in three-dimensional space. Hence, this two N-localizer configuration is susceptible to error. The present article proposes the V-localizer that comprises multiple diagonal bars to provide four or more non-colinear points to minimize error.
Highlights
Image-guidance for frame-based stereotaxis is facilitated by incorporating three to four N-localizers or Sturm-Pastyr localizers into a stereotactic frame [1,2]
Monte Carlo (MC) simulation [3] predicts that the attachment of one N-localizer to each of the anterior, posterior, and left and right lateral faces of a rectangular stereotactic frame affords the highest accuracy [4]
To avoid contact with the computed tomography (CT) scanner couch, the posterior N-localizer is often omitted, which results in a configuration that comprises three N-localizers [4]
Summary
Image-guidance for frame-based stereotaxis is facilitated by incorporating three to four N-localizers or Sturm-Pastyr localizers into a stereotactic frame [1,2]. This transformation is accomplished by a 3-by-3 matrix that is computed from the (x, y, z) coordinates of three points (each of which lies on the long axis of a diagonal bar) together with the (u, v) coordinates of the centroids of three corresponding fiducials created by the respective diagonal bars [8]. This approach may be extended to improve the RMSe by defining an overdetermined system of linear equations, the solution to which is the 3-by-3 transformation matrix [4].
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